How Long Does Horse Chestnut Take To Work? (Solved)

It may take up to 4 weeks before your symptoms improve. Call your doctor if your symptoms do not improve, or if they get worse while using horse chestnut.

How long does it take for horse chestnut to work?

  • It is best to use a horse chestnut product that contains an exact amount of the labeled chemical. Check the label to be sure your product does not contain a toxic substance called “esculin.” It may take up to 4 weeks before your symptoms improve. Call your doctor if your symptoms do not improve, or if they get worse while using horse chestnut.

How long should horse chestnut be taken?

Dosing. Horse chestnut extract has most often been used by adults in doses of 300-600 mg by mouth daily for 8-12 weeks.

What does horse chestnut do for the body?

Horse chestnut extract has powerful anti-inflammatory properties and may help relieve pain and inflammation caused by chronic venous insufficiency (CVI). It may also benefit other health conditions like hemorrhoids and male infertility caused by swollen veins.

Does horse chestnut help prevent blood clots?

The seed of the horse chestnut is a small brown nut. Unprocessed horse chestnut seeds contain a toxin called esculin (also spelled aesculin). This toxin may increase the risk of bleeding due to its ability to prevent blood clots from forming.

Can horse chestnut reverse varicose veins?

Does Horse Chestnut really work to treat Varicose Veins? Probably yes. Randomized studies in which horse chestnut extract is compared with a placebo (sugar pill) show a significant improvement in pain. In addition, most of the studies also show an improvement in swelling.

Is horse chestnut good for hair growth?

Horse chestnut lotions and creams have been used by traditional healers to speed healing of blunt sports injuries; the herb has also been used to treat aging skin, cellulite, and hair loss, though little research exists to support that its active compounds are absorbed through the skin.

Does horse chestnut cream get rid of spider veins?

Horse Chestnut This herb has long been linked to the reduction of inflammation and the strengthening of vessel walls. Like vitamin K solutions, horse chestnut may successfully disguise the appearance of spider veins due to its anti-inflammatory properties.

Is chestnut good for weight loss?

Chestnuts are high in fiber, which may help you lose weight by slowing down the digestion of food and curbing your appetite. They also contain fewer calories than other varieties of nuts due to their low fat content.

Is horse chestnut good for skin?

Horse chestnut’s benefits for the skin do not stop at saponins – the seed extract contains a number of flavonoids (powerful antioxidants) such as quercetin, kaempferol, and rutin, that have demonstrated wound healing, anti-inflammatory, and anti-enzymatic properties.

Is chestnut good for thyroid?

As water chestnut contains useful minerals like iodine and manganese, it helps in maintaining proper functioning of the thyroid gland.

Does horse chestnut raise blood pressure?

Horse chestnut extract appears to impair the action of platelets (important components of blood clotting). It also inhibits a range of chemicals in the blood, including cyclo-oxygenase, lipoxygenase and a range of prostaglandins and leukotrienes. These effects result in reduced inflammation and reduced blood pressure.

Why is it called horse chestnut?

Etymology. The common name horse chestnut originates from the similarity of the leaves and fruits to sweet chestnuts, Castanea sativa (a tree in a different family, the Fagaceae), together with the alleged observation that the fruit or seeds could help panting or coughing horses.

What eats horse chestnuts?

There are some animals that can safely eat conkers. These include wild boars and deer. However, they are too toxic for humans to eat and will make people unwell. Strangely, despite the name horse chestnuts, they are also poisonous for horses.

Is walking good for venous insufficiency?

Exercise is a surprisingly effective treatment for venous insufficiency. Exercising gets your heart pumping, and the extra pumping force of your heart pushes the blood up and out of your lower legs. Walking is particularly beneficial.

How can I open clogged veins in my legs naturally?

If a person has varicose veins, they can try the following home remedies to help manage the condition and improve symptoms:

  1. Exercise.
  2. Compression stockings.
  3. Plant extracts.
  4. Dietary changes.
  5. Eat more flavonoids.
  6. Herbal remedies.
  7. Choose non-restrictive clothing.
  8. Keep the legs elevated.

What are the stages of varicose veins?

Sun City Vein Doctors Explain the Stages of Vein Disease, and Why You Want To Seek Early Treatment

  • Stage one – spider veins.
  • Stage two – enlarged, ropy varicose veins.
  • Stage three – edema (swelling), but without skin changes.
  • Stage four – skin changes and discoloration.
  • Stage five – skin changes with healed ulceration.

Horse chestnut seed extract for long-term or chronic venous insufficiency

Conclusions of the authors: Based on the evidence given, HCSE appears to be an effective and safe short-term therapy for CVI. Many limitations remain, and bigger, definitive randomized controlled trials are needed to prove the effectiveness of this therapy approach. See the complete abstract for more information. Background: The conservative treatment of chronic venous insufficiency (CVI) relies mostly in the use of compression. However, this frequently causes pain and has been linked to lower levels of patient compliance.

Presented below is an updated version of a Cochrane review that was initially published in 2002 and has since been revised in 2004, 2006, 2008, and 2010.

The following is the search strategy: The Cochrane Peripheral Vascular Diseases Review Group checked their Specialised Register (which was last searched in June 2012) and the CENTRAL database for this update (Issue 5, 2012).

HCSE preparation manufacturers and subject matter experts were approached for both published and unpublished material on the subject of HCSE.

  1. The following are the selection criteria: Randomized controlled trials comparing oral HCSE mono-preparations with placebo or reference treatment in persons with CVI were conducted.
  2. Data collection and analysis are two important aspects of every research project.
  3. Through dialogue, disagreements on the assessment of particular experiments were addressed.
  4. Leg pain was evaluated in seven randomized, placebo-controlled studies.
  5. The results of one study indicated a weighted mean difference (WMD) of 42.4 mm (95% confidence interval (CI) 34.9 to 49.9) when assessed on a 100 mm visual analogue scale.
  6. A WMD of 32.1ml (95 percent confidence interval: 13.49 to 50.72) was seen in six studies (n = 502) in favor of HCSE when compared to placebo.

According to the results of one study, HCSE may be just as effective as therapy with compression stockings. The majority of adverse effects were moderate and uncommon.

Horse chestnut Uses, Side Effects & Warnings

Horse chestnut is the generic name for this plant (HORSE CHEST nut) Venastat is the brand name for this product. Oral capsules are the most common dosage type (300 mg) Herbal products are a type of medication.

  • Indications, precautions, and instructions
  • What to avoid
  • Side effects and interactions

What is horse chestnut?

Aescin, Aesculus hippocastanum, Castao de Indias, Châtaignier de Mer, Châtaignier des Chevaux, Escine, Faux-Châtaignier, Hippocastani, Hippocastanum Vulgare Gaertn, Marron Europeen, Marronnier, Spanish Chestnut, Venostasin Retard, Venostat, White Chestnut, and other names are all used to describe this Equine chestnut has traditionally been utilized in alternative medicine, and it is believed to be useful in alleviating some signs and symptoms associated with chronic venous insufficiency (decreased blood flow return from the feet and legs back to the heart).

  • Leg soreness or tenderness, varicose veins, itching or swelling in the legs, and fluid retention are some of the signs of this condition (puffy or swollen ankles or feet).
  • It is not known whether horse chestnut is beneficial in the treatment of any medical disease, including cancer.
  • In addition, horse chestnut should not be substituted for any prescription recommended by your doctor.
  • Because there are currently no controlled manufacturing standards in place for a large number of herbal substances, several advertised supplements have been found to be contaminated with harmful metals or other medications.
  • Horse chestnut can be used for a variety of other uses that are not covered in this product reference.


All product labeling and packaging instructions must be followed. Inform each of your healthcare providers about all of your medical problems, allergies, and medications that you are currently taking.

Before taking this medicine

Consult your healthcare physician before beginning to use horse chestnut. If you have specific medical issues, such as the following, you may not be able to utilize horse chestnut:

  • If you have a bleeding or blood clotting disorder (horse chestnut can thin your blood), diabetes (horse chestnut can cause low blood sugar), kidney disease, liver disease, a stomach or intestinal disorder, congestive heart failure, epilepsy, asthma, migraine headaches, or if you are allergic to latex, you should avoid using horse chestnut products.

Uncertainty exists as to whether horse chestnut will do damage to an unborn child. If you are pregnant, you should avoid using this product. Horse chestnut has the potential to transfer into breast milk, causing damage to a breastfeeding baby. If you are breast-feeding a child, you should avoid using this product. Do not offer any herbal or health supplement to a child unless you have obtained medical advice beforehand.

How should I use horse chestnut?

In the event that you are considering the use of herbal supplements, consult with your doctor first. You could also think about talking with a practitioner who is well-versed in the usage of herbal remedies and health supplements. If you decide to use horse chestnut, follow the directions on the container or those given to you by your doctor, pharmacist, or other healthcare practitioner. Make sure you do not use more of this product than what is indicated on the package. If you take horse chestnut in capsule form, the normal dose is 1 capsule every 12 hours before a meal before bed.

Horse chestnut capsules should not be crushed, chewed, broken, or opened in any way.

Use a horse chestnut product that includes an exact amount of the stated ingredient in order to achieve the greatest results.

It might take up to 4 weeks for your symptoms to begin to ease. If your symptoms do not improve or if they worsen while taking horse chestnut, consult your doctor. Moisture, heat, and light should all be avoided when storing this product.

What happens if I miss a dose?

If it is almost time for your next scheduled dosage, you should skip the missed dose. It is not necessary to take more horse chestnut to make up for the missing dose.

What happens if I overdose?

Seek immediate medical treatment or dial 1-800-222-1222 to reach the Poison Help hotline for assistance. The usage of raw horse chestnut (seeds, blossoms, stems, and leaves) can result in deadly toxicity if consumed in large quantities. Strength, low mood, loss of coordination, dilated pupils, vomiting and diarrhea, infrequent or no urination, muscular twitching, and loss of mobility in any region of the body are all possible symptoms of horse chestnut poisoning.

What should I avoid while taking horse chestnut?

Raw horse chestnut seed, bark, blossom, or leaves should be avoided at all costs. These products are not safe to consume orally and may have potentially catastrophic negative effects. Horse chestnut should not be taken in conjunction with other herbal/health supplements that might reduce blood sugar levels, such as alpha-lipoic acid, chromium, devil’s claw, fenugreek, garlic, guar gum, Panaxginseng, psyllium, and Siberian ginseng, among others. It is best not to use horse chestnut with other herbs or health supplements that might interfere with blood clotting time.

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Horse chestnut side effects

If you have any of the following symptoms of an allergic reaction, get medical attention immediately: hives; difficulty breathing; swelling of your face, lips, tongue, or neck. Horse chestnut is regarded to be potentially harmless when consumed for a short length of time, despite the fact that not all of its adverse effects are known. If you develop any of the following symptoms, stop taking horse chestnut and contact your healthcare professional right away: The following are examples of common side effects: The following is not a comprehensive list of possible side effects, and more may occur.

You can report adverse effects to the Food and Drug Administration at 1-800-FDA-1088.

What other drugs will affect horse chestnut?

If you are using any of the drugs listed below, you should not take horse chestnut without seeing your doctor first.

  • In addition to insulin or an oral diabetes medication, you may need blood clot-prevention medications such as clopidogrel (Plavix), dabigatran (Enoxaparin), heparin (Coumadin, Jantoven), and others
  • Or an NSAID (nonsteroidal anti-inflammatory drug) such as aspirin, ibuprofen (Advil,Motrin), naproxen (Aleve), celecoxib (dic

This is not an exhaustive list. Other medications, including prescription and over-the-counter medications, vitamins, and herbal supplements, may have an adverse reaction with horse chestnut. This product guide does not provide a comprehensive list of all potential interactions.

Further information

  • If you are considering utilizing any herbal or health supplement, consult with a registered healthcare expert first. In order to ensure that all of your healthcare providers are aware of all of your medical issues and medications, whether you are being treated by a medical doctor or a practitioner educated in the use of natural medicines/supplements, you should:

Remember to keep this and all other medications out of the reach of children, never share your medications with others, and only use this drug for the indication that has been given for it. Always check with your healthcare practitioner to confirm that the information contained on this page is accurate and applicable to your specific situation. Disclaimer on Medical ImplicationsCopyright 1996-2022 Cerner Multum, Inc. version 3.02 is available.

7 Health Benefits of Horse Chestnut Extract

Horse chestnut, also known as Aesculus hippocastanum, is a kind of tree that is indigenous to the Balkan Peninsula. It is often used to promote vascular health and reduce inflammation. Horse chestnut seed extract is a popular nutritional supplement that is derived from the horse chestnut seed. Aescin is the primary active ingredient in horse chestnut extract, and it has been extensively researched for its numerous health advantages.

Listed below are seven health advantages associated with horse chestnut extract. We feature goods that we believe will be of interest to our readers. If you make a purchase after clicking on one of the links on this page, we may receive a small commission. Here’s how we went about it.

1. May relieve symptoms of chronic venous insufficiency

Chronic venous insufficiency (CVI) is a medical disorder that is characterized by insufficient blood flow to the veins of the lower extremities (legs). Among the signs and symptoms are (1):

  • Edema, or swelling of the legs
  • Leg discomfort or cramps
  • Itchy legs
  • Varicose veins, or swollen, twisted veins that often appear in the legs
  • Leg ulcers
  • And weakness in the legs are all symptoms of venous disease.

Compression therapy, often known as stockings, is a popular treatment that can help to enhance blood flow to your legs. Horse chestnut has a chemical called aescin, which has a variety of therapeutic qualities that might make it effective in the treatment of CVI. For example, it may enhance blood flow in your veins, which may result in symptoms being alleviated ( 2 , 3 , 4 ). After reviewing 19 trials, researchers discovered that daily dosages of 600 mg of horse chestnut extract containing 50 mg of the anti-inflammatories aescin, administered for up to 8 weeks, significantly decreased symptoms of CVI such as leg discomfort, edema, and itching (5).

According to these studies, horse chestnut extract may be useful in the short term for the treatment of CVI; however, further study is needed to assess its long-term effects.

2. May treat varicose veins

A varicose vein is an abnormally enlarged, bulging vein that commonly develops in the legs and can be caused by chronic venous insufficiency (CVI). Horse chestnut seed extract may help to enhance venous tone in your legs by increasing blood flow to them ( 7 , 8 ). Aside from that, it may be beneficial in reducing leg swelling and discomfort associated with vein disease ( 2 ). Participants in an 8-week study who took horse chestnut seed extract tablets containing 20 mg of Aescin three times daily and applied 2 percent aescin gel topically twice daily reported a reduction in varicose vein symptoms such as leg pain, swelling, heaviness, and discoloration, according to the findings ( 4 ).

3. Has potent anti-inflammatory properties

It is possible that inflammation can induce an excessive accumulation of fluid in your tissues, which will result in fluid retention and edema ( 9 ). In horse chestnut extract, there is a compound called aescin, which has anti-inflammatory qualities. According to research, it can help to decrease inflammation associated with injury, venous insufficiency, and edema ( 10 , 11 , 12 , 13 ). According to the findings of a review of 17 research, horse chestnut seed extract may be effective in reducing inflammation and edema in the legs and feet associated with CVI ( 2 ).

However, because this ointment also contains other anti-inflammatory components, it is uncertain if aescin on its own would have the same benefits as other anti-inflammatory substances.

Summing UpInflammation can result in edema and fluid retention in the body. Blood vessel inflammation caused by chronic venous insufficiency, trauma, surgery, or traumas may be reduced by horse chestnut seed extract (HCSE).

4. May relieve hemorrhoids

A frequent health ailment characterized by swollen veins surrounding your anus and rectum, hemorrhoids are an unpleasant and uncomfortable experience. The symptoms are unpleasant and might include itching, discomfort, pain, and rectal bleeding, among other things ( 16 ). The anti-inflammatory qualities of horse chestnut seed extract may aid in the relief of hemorrhoid symptoms by lowering inflammation and swelling in the afflicted veins, according to research ( 17 ). Despite this, research in this area is limited, and further studies are needed to prove the potential advantages of horse chestnut extract for the treatment of hemorrhoids in the long term.

5. Has antioxidant properties

It includes potent antioxidants, which are substances that can help prevent cell damage produced by unstable molecules known as free radicals. Horse chestnut seed extract has a high concentration of antioxidants. An excessive amount of free radicals can cause inflammation and cellular damage ( 18 ). Horse chestnut seed extract has a high concentration of flavonoid components, such as quercetin and kaempferol, both of which are known to have powerful antioxidant capabilities ( 19 ). The antioxidant qualities of aescin and horse chestnut seed extract were discovered in a test-tube investigation; however, the horse chestnut seed extract was shown to be significantly more effective than aescin alone.

SummaryHorse chestnut seed extract includes antioxidants that may be useful in protecting against cellular damage produced by free radicals in the environment.

6. Contains cancer-fighting compounds

Besides having potent anti-inflammatory qualities, research in test tubes has revealed that aescin may potentially have anti-cancer characteristics as well. According to the findings of these research, aescin has the potential to drastically inhibit tumor cell development in diseases such as liver cancer, leukemia, and multiple myeloma ( 21 , 22 ). Additional research has discovered that aescin can trigger cell death in malignant cells such as pancreatic cancer and lung cancer in test-tube trials as well ( 23 , 24 ).

It will need more human investigations in this area before any definitive conclusions can be drawn.

Nonetheless, further study in this area is required before conclusive findings can be reached.

7. May help with male infertility

Varicocele, or enlargement of the veins surrounding the testicles, is one of the factors that contribute to male infertility ( 25 ). Horse chestnut extract, known as aescin, has anti-inflammatory and anti-swelling qualities that may make it a useful therapy for infertility caused by varicocele, according to recent research ( 26 , 27 ). More than 100 men with varicocele-associated infertility were studied over the course of two months, and it was shown that taking 30 mg of aescin every 12 hours enhanced sperm density as well as sperm motility and quality.

Infertility can be caused by swelling of the veins around the testicles, according to the summary. The presence of a specific component in horse chestnut extract has been shown to increase sperm quality and reduce varicocele in males suffering from varicocele-associated infertility.

Safety and side effects

While the usage of horse chestnut seed extract is generally believed to be safe, you should be aware of certain potential safety issues and side effects when using this supplement. According to the Food and Drug Administration, horse chestnut seeds that have not been treated contain a chemical called aesculin, which should not be consumed in any form (FDA). Depression, muscular twitching, paralysis, coma, and death are all possible symptoms of poisoning ( 3 ,29). Consequently, raw horse chestnut seeds should be avoided at all costs.

Additionally, when horse chestnut extract has been administered to the skin, there have been instances of allergic responses to the substance ( 2 , 30 ).

  • Blood thinners are medications that thin the blood. Horse chestnut may cause blood coagulation to slow down and the effects of blood thinners such as Coumadin, insulin, and oral diabetic medications to be enhanced. When used with diabetic medication, horse chestnut may cause blood sugar levels to drop too low, resulting in hypoglycemia. Nonsteroidal anti-inflammatory medications (NSAIDs) (NSAIDs). Horse chestnut may help to limit the absorption of nonsteroidal anti-inflammatory medicines (NSAIDs), which are medications used to treat inflammation. Lithium. According to some reports, horse chestnut may have a diuretic impact, which may cause your body to metabolize lithium more slowly, which is used to treat mental problems

Furthermore, persons suffering from renal or liver illness should avoid consuming horse chestnut since it may increase the symptoms of their sickness ( 3 ). In light of these considerations, you should always discuss with your healthcare professional before using horse chestnut extract, particularly if you have a medical condition or are presently taking medication. Women who are pregnant or nursing should avoid using horse chestnut extract because the supplement’s safety during these times is uncertain.

However, there have been some reports of adverse effects, interactions with specific drugs, and safety issues connected with certain medical conditions, all of which should be taken into consideration.


Horse chestnut is available in a variety of forms in shops and on the internet, including capsules, pills, liquid drops, essential oil, and cream. Aescin is found in horse chestnut extract in concentrations ranging from 16 to 20%. The most often used dose of aescin is 100–150 mg per day, according to the results of most investigations. As a result, the possible hazardous consequences of greater dosages are yet unclear. Consequently, it is recommended that you follow the dose directions provided ( 2 , 30 ).

There is no established guideline for liquid dietary supplements at the present time.

Extractions and creams that are administered topically often contain 2 percent aescin and can be applied three to four times per day ( 2 , 30 ).

The bottom line

With its substantial anti-inflammatory qualities, horse chestnut extract has the potential to help reduce the pain and inflammation produced by chronic venous insufficiency (CVI). It may also be beneficial for other health disorders such as hemorrhoids and male infertility, which are both caused by enlarged veins in the legs. Horse chestnut is a popular natural remedy for a number of diseases because of its anti-inflammatory and antioxidant characteristics.

Although the extract is generally believed to be safe to consume, it may have negative effects and may interact with some prescription drugs. As a result, before consuming horse chestnut extract, talk to your doctor or other healthcare expert.

Horse Chestnut for Varicose Veins

Horse Chestnut is a kind of tree that may be found throughout Europe and the United States of America. The bark from young branches and the seeds of the tree are the parts of the tree that are utilized in medicine. The seeds that are found inside the fruit are seen in the image below. If the seeds are not processed, they are toxic. Aescin, on the other hand, is one of the compounds contained in horse chestnut seed. It is the compound Aescin, which is isolated from the horse chestnut seed, that may be beneficial for circulatory health.

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How Does Horse Chestnut Treat Varicose Veins?

Aescin has three effects that are beneficial in the treatment of symptoms of venous insufficiency.

  • First and foremost, it reduces edema or swelling. Chronic venous insufficiency leads in capillary leakage of plasma fluid as a result of elevated venous pressure in the legs. Edema or swelling occurs as a result of this leak. Aescin has a “sealing” effect on tiny blood vessels
  • Second, it has anti-inflammatory properties as well. Aescin operates at the cellular level to inhibit the release of inflammatory mediators
  • Finally, it enhances the tone of the veins and capillaries. When exposed to Aescin, the smooth muscle in normal vein walls contracts, indicating that the vein is healthy.

Does Horse Chestnut really work to treat Varicose Veins?

Most likely, yeah. Horse chestnut extract, when compared to a placebo (a sugar tablet), has been shown to provide a substantial reduction in pain in randomized experiments (see below). Furthermore, the majority of the trials have shown a reduction in edema as well. Another research of venous stasis ulcer patients found no improvement with Aescin, despite the fact that the drug was prescribed. As a result, it is suggested that Horse Chestnut is less helpful when the condition is advanced.

There are so many different preparations of Horse Chestnut, which one is best?

  • The pill is the form that has been examined the most. Creams and lotions have poor absorption through the skin and are thus not suggested
  • Look for the active component Aescin in these formulations. The recommended daily dose of Aescin is around 100-150mg divided into two doses. This is when a little math comes into play. If the preparation contains 300 mg of Horse Chestnut and the amount of Aescin is 20%, it equates to 60 mg of Aescin per tablet. Dietary supplements are not regulated by the FDA. Therefore, search for a supplement that has been manufactured according to Good Manufacturing Practices (GMP).

So, Horse Chestnut works, why not use it?

  • Using horse chestnut for more than 6 months is not suggested because it has a limited half-life. Using Horse Chestnut to treat chronic venous insufficiency merely serves to delay the need for a more permanent solution
  • Horse Chestnut does not appear to be effective in treating severe illness, which is a concern. When the illness progresses, vessel wall deterioration develops, and fibrous tissue takes the place of the muscles. Aescin, on the other hand, will alleviate the symptoms of chronic venous insufficiency by boosting venous tone and avoiding leaks. When you have varicose veins, you will experience swelling, discomfort, and itching. Aescin does not necessarily improve one’s look
  • After all, it is a pharmaceutical product. Despite the fact that it is a supplement and that it originates from nature, it has been synthesized into an active chemical and is thus classified as a drug. This is similar to opium and other drugs, which are derived from poppy seeds and processed into pills. Additionally, it is similar to aspirin, which was initially derived from willow bark. As a result, as with any medication, you should consult with your doctor before using it.

Bottom Line

Horse Chestnut extract is effective in alleviating the symptoms of chronic venous insufficiency when used on a short-term basis. Horse Chestnut extract, on the other hand, will not assist with advanced sickness. Horse Chestnut extract, on the other hand, is a pharmaceutical. Consult your doctor before using this product.


A study of horse-chestnut seed extract for chronic venous insufficiency was conducted by Pittler and Ernst. A criterion-based systematic review was conducted. Arch Dermatol. 1998 Nov;134(11):1356-1360 [Arch Dermatol]. B Human varicose saphenous veins respond to vasoactive agents in the presence of runner’s factor (F), Christine (H), and Schuller-Petrovic (S). The British Journal of Clinical Pharmacology published a paper in March 2001 titled “Br J Clin Pharmacol 51(3):219-224.” Clinical effectiveness of horsechestnut seed extract in the treatment of venous ulcers, Leach MJ, Pincombe J, Foster G, Journal of Medicinal Food, vol.

Sirtori C.

Pharmacological Research, vol.

3, pp.

How long does horse chestnut take to work?

Overall, the results of the studies indicated that horse chestnut seed extract, taken as capsules over a period of two to sixteen weeks, might alleviate the symptoms of leg discomfort, oedema, and pruritus. Continue reading for the whole response. Horse chestnut extract appears to have a negative effect on platelet function (important components of blood clotting). A variety of molecules in the blood are also inhibited by it, including cyclo-oxygenase, lipoxygenase, and a variety of prostaglandins and leukotrienes, among other things.

  1. Aside from that, what is it that horse chestnut does for the body?
  2. A 300-mg daily dose of standardized horse chestnut seed extract can help to alleviate certain symptoms of poor blood circulation, such as leg edema, varicose veins, soreness, and fatigue.
  3. Likewise, For how long does butcher’s broom operate before it becomes ineffective?
  4. Also, What are the possible adverse effects of horse chestnut consumption?
  5. Allergies to pollen from the horse chestnut blossom have been reported in the past.
  6. Is it true that horse chestnut cream is effective?

Long-term studies are required due to the fact that therapy for this ailment will need to be continued for many years. In short-term tests, the extract was found to be safe.

19 Related Question Answers Found

Butcher’s Broom is a plant that belongs to the Asparagus family (Asparagaceae), and its berries are toxic, as is the plant itself. In the event that they are consumed, they might induce digestive difficulties as well as hemolysis, which is the rupturing or destruction of red blood cells.

How long does it take for horse chestnut to work?

Overall, the results of the studies indicated that horse chestnut seed extract, taken as capsules over a period of two to sixteen weeks, might alleviate the symptoms of leg discomfort, oedema, and pruritus.

What happens if you eat horse chestnuts?

When eaten raw, horse chestnut contains considerable levels of esculin, a toxin that can be fatal if consumed in large quantities. Make sure you don’t confuse Aesculus hippocastanum (Horse chestnut) with Aesculus californica (California buckeye) or Aesculus glabra (Silver buckeye) when looking for horse chestnut (Ohio buckeye).

Are horse chestnuts edible for humans?

Horse chestnuts, commonly known as conkers, are a kind of nut that is quite distinct. Is it possible to eat horse chestnuts? They aren’t, in fact. It is generally recommended that horse chestnuts should not be ingested by humans or other animals, such as horses or other livestock.

What does Butcher’s Broom do for the body?

Butcher’s broom is a herb that is often used to treat symptoms of poor blood circulation, such as soreness, leg cramps, leg swelling, varicose veins, itching, and swelling in the feet. Although butcher’s broom is commonly used topically, it is also used orally for kidney stones, gallstones, “hardening of the arteries” (atherosclerosis), constipation, and a variety of other ailments.

How effective is horse chestnut for varicose veins?

Inflammation of the veins and other circulatory issues (chronic venous insufficiency). Taking horse chestnut seed extract, which contains 16 percent to 20 percent of the chemical aescin, can help to alleviate some of the symptoms of poor blood circulation, such as varicose veins, soreness, fatigue, swelling in the legs, itching, and water retention in the body.

Can horse chestnuts kill you?

“They’re really toxic.” Nonetheless, unless you consume a large quantity of horse chestnuts, they are more likely to cause illness than death. A report on the Nova Scotia Museum’s website states that while horse-chestnut poisoning is seldom deadly, the symptoms can include vomiting, loss of coordination, stupor, or even paralysis in severe cases, according to the site.

Does horse chestnut lower blood pressure?

Horse chestnut extract appears to have a negative effect on platelet function (important components of blood clotting). A variety of molecules in the blood are also inhibited by it, including cyclo-oxygenase, lipoxygenase, and a variety of prostaglandins and leukotrienes, among other things. These actions lead to a reduction in inflammation as well as a reduction in blood pressure.

Does horse chestnut affect blood pressure?

Blood platelets appear to be impaired by horse chestnut extract, according to certain studies (important components of blood clotting).

As well as inhibiting cyclo-oxygenase and lipoxygenase, it also has inhibitory effects on a number of other compounds in the blood, including a variety of prostaglandin and leukotrienes. Consequently, inflammation is minimized, and blood pressure is brought down.

Is horse chestnut tree poisonous?

Because of the presence of esculin in raw horse chestnut seed, leaf, bark, and flower, these parts of the plant should not be consumed. The FDA has designated horse chestnut seed as a potentially dangerous botanical. Toxic substances include the glycoside and saponin components of the compound.

Does butcher’s broom help hemorrhoids?

It is possible to reduce your risk of hemorrhoids. The results of one study showed that 69% of those who used butcher’s broom supplement thought it was a successful therapy for hemorrhoids, as measured by the reduction of their discomfort, puffiness, and other symptoms (13).

What is Ruscus extract?

Some People Make Use Of Butcher’s Broom is used to treat Chronic Venous Insufficiency (CVI). A little evergreen shrub native to Europe and North Africa, butcher’s broom, or Ruscus aculeatus, is used to make butcher’s broom herb. The plant’s root is utilized to create the nutritional supplement. In various parts of the world, these roots are consumed in the same way as asparagus is. 14 days ago – This page was last updated. The following are the co-authors: 7 – users: 11

What Is Horse Chestnut?

Well, Anastasia Tretiak, you’ve done really well. An Aesculus hippocastanum (horse chestnut) is a kind of tree that may be found growing across the Northern Hemisphere. Horse chestnut seed, leaves, bark, and blossoms have long been used in herbal and folk medicine to alleviate symptoms such as swelling and inflammation, as well as to strengthen blood vessel walls and to improve circulation. According to the horse chestnut’s health claims, it can be used to cure the following conditions:

  • Circulatory problems, diarrhea, hemorrhoids, and varicose veins are among conditions that might occur.

Horse chestnut includes a chemical component known as aescin, which has been shown to have anti-inflammatory effects on the body. Esculin, which is found in the unprocessed seeds, leaves, bark, and flowers, among other things, is toxic and may increase the risk of bleeding. (Aescin, on the other hand, is a separate chemical that is generally thought to be safe.) Esculin can be eliminated from the body. Esculin is removed from horse chestnut seed extract that has been properly processed.

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What Is Horse Chestnut Used For?

Horse chestnut has been shown to be beneficial in the treatment of chronic venous insufficiency in humans and animals (CVI). CVI is a disorder in which the veins in the legs are unable to adequately return blood from the legs to the heart. It has been associated to issues such as varicose veins, ankle swelling, and nightly leg cramps among other things. There has been very little study done on horse chestnut for the treatment of other ailments.

Chronic Venous Insufficiency

According to recent research, horse chestnut seed extract may be beneficial in the treatment of CVI. People suffering with CVI reported reduced leg discomfort, swelling, and itching when they were given horse chestnut seed extract for a short period of time, according to a systematic evaluation of 12 clinical studies published in 2012. The researchers came to the conclusion that “the data provided shows that horse chestnut seed extract is an effective and safe short-term therapy for CVI,” according to the findings.

As reported by the National Center for Complementary and Integrative Health, there is currently insufficient data to demonstrate the positive effects of horse chestnut on disorders other than CVI. Verywell Anastasia Tretiak is a writer who lives in New York City.

Selection, Preparation,Storage

Never consume any part of the horse chestnut tree, including the nuts. A poisoning from the herb’s fresh, unprocessed parts (which may include its leaves, bark, or blossoms) can result in illness if consumed. Instead, spend your money on a commercial supplement. Esculin, a poisonous component of horse chestnut goods, is removed during the manufacturing process. In spite of the fact that these products are extensively used in Europe, there have been very few reports of serious side effects associated with them.

Dose: 50 milligrams of aescin twice or three times a day is the most commonly prescribed dosage.

Possible Side Effects

Horse chestnut extract has been shown to cause a variety of negative side effects, including itching, nausea, and gastrointestinal difficulties, as well as muscular pains and headaches in some people. If you’re thinking of using horse chestnut to treat CVI or any chronic health issue, talk to your doctor first to be sure you’re not doing anything harmful to your body. Horse chestnut should be avoided by people who have renal or liver problems, as well as bleeding issues. Unless under medical supervision, horse chestnut should not be used in conjunction with aspirin, Plavix (clopidogrel) and Coumadin (warfarin), or other anticoagulant or anti-platelet (blood-thinning) medicines since it may enhance the action of these treatments.

Keep in mind that there hasn’t been any research done on the safety of supplements in pregnant women, nursing mothers, children, and people who have medical issues or who are taking drugs.

Frequently Asked Questions

  • Do you know if horse chestnut is good for your kidneys? People with healthy kidneys should be able to use horse chestnut supplements in modest dosages without experiencing any adverse effects. People with renal or liver illness, on the other hand, should avoid taking horse chestnut. What is the effect of horse chestnut on your legs? A supplement containing horse chestnut seed extract may be beneficial in the treatment of chronic venous insufficiency (CVI), a circulatory disorder associated with varicose veins, ankle swelling, and nightly leg cramps. According to research, horse chestnut can help persons suffering from CVI with their leg discomfort, swelling, and itching. Is horse chestnut a dangerous plant to eat? Yes, horse chestnut in its raw, uncooked form may be lethal. Ingesting unprocessed portions of the horse chestnut tree, such as the leaves, bark, or blossoms, can result in illness and perhaps poisoning if done so repeatedly. Esculin, a toxic substance found in the horse chestnut tree, is responsible for the tree’s deadly properties. Supplements sold in stores have been treated to eliminate esculin and are thus safe to take.

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How long can you take horse chestnut extract?

Taking horse chestnut seed extract as capsules for two to sixteen weeks seems to be effective in alleviating the symptoms of leg discomfort, oedema, and pruritus in the majority of the participants. Summary Taking 100–150 mg of aescin per day in supplement form and 3–4 applications of cream or extract per day when applied topically appears to be the most helpful dose for horse chestnutseed extract. As a result, the issue is, what are the benefits of horse chestnut pills? It has been used in alternative medicine and is likely to be useful in treating some symptoms of chronic venous insufficiency, according to some studies (decreased blood flow return from the feet and legs back to the heart).

Esculin is removed from horse chestnutseedextract after it has been properly processed.

Despite this, several adverse effects have been reported, including itchiness, nausea, gastrointestinal disturbance, muscular spasms, and headaches.

Horse chestnut has a chemical that has the effect of thinnining the blood. This medication also helps to minimize water retention by making it more difficult for fluid to seep out of veins and capillaries, as well as weakly encouraging fluid excretion through the urine (edema).

Horse Chestnut

HORSE CHESTNUT, also known as buckeye and Spanish chestnut, is a kind of tree whose fruits (seeds, leaves, bark, and blossoms) have been used medicinally for thousands of years. The trees are native to Eastern Europe, however they may be found all across the Northern Hemisphere due to their widespread distribution. It is commonly called to as buckeye, however it is not the same species as buckeye trees that grow in Ohio and California, despite the fact that it looks similar. Horse chestnut seed extract has been widely explored for the treatment of chronic venous insufficiency (CVI), a circulatory disorder in which the veins fail to adequately return blood from the legs to the heart (see below).

Varicose veins are also present.

According to one research, it is just as efficient as compression stockings in terms of reducing swelling.

Symptoms of discomfort, itching, burning, and swelling were greatly reduced in one small trial that used horse chestnut extract.

Aescin extracts standardized to contain 16 to 20% aescin are available in the following forms: Interactions between herbs and medications: The use of horse chestnut extract may cause bruising and bleeding in patients who are taking aspirin, ibuprofen, coumadin, or other medicines that reduce blood coagulation, according to the American College of Nutrition.

  1. Lithium is a medication used to treat the manic phase of the disease.
  2. Horse chestnut has been shown to reduce blood sugar levels in diabetics, which may enhance the benefits of diabetes medications that lower blood sugar levels.
  3. Aesculin is a compound in horse chestnut seeds, leaves, bark, and flowers that is poisonous if consumed in teas or remedies made with raw or unprocessed horse chestnut seeds, leaves, bark, or flowers.
  4. It is believed that horse chestnut seed extract, when properly processed, has little or no aesculin and is hence safe for short-term usage.
  5. It has not been determined whether or whether using horse chestnut is safe for women who are pregnant or who are nursing.
  6. Purchase items with an aescin level of 16 to 20% and follow the guidelines on the label when preparing meals or cooking.
  7. Dosage for children: It has not been determined whether horse chestnut is safe for youngsters to consume.
  8. Weil explains.
  9. The chemical aescin is regarded to be the primary active element in HCSE, as it contributes to the maintenance of normal vessel-wall function.
  10. The active components in the seeds appear to prevent enzymes that might cause damage to capillary walls, which in turn appears to help strengthen veins.

SOURCES: cs=NONMP s=NDC pt=100 id=1055 fs=NDC searchid=45802997 s=NDC pt=100 id=1055 s=NDC searchid=45802997 J.

  1. Gillet, J.M.
  2. Defrance.
  3. Rev Med Liege 1976;31:343–345 (in French).
  4. Pittler MH, Ernst E.
  5. Cochrane Database Syst Rev.
  6. Natural Medicines Comprehensive Database,, accessed March 27, 2014.

Horse chestnut. Natural Medicines Comprehensive Database, accessed March 27, 2014. New York University Langone Medical Center’s Principle Proposed Usages for Horse Chestnut The 27th of March, 2014

Why horse chestnut treatment is not in vein

DOES IT ACTUALLY WORK: According to Dónal O’Mathna, horse chestnut extract has been used to treat varicose veins with a decent amount of effectiveness in the past. HORSE CHESTNUT TREE: The horse chestnut tree is the most widespread kind of chestnut tree in Ireland. The nuts that fall at this time of year can be just as tasty as conkers, but they should not be consumed as such. When you think of Christmas, the phrase “chestnuts cooking over an open fire” conjures up romantic images of the season.

However, an extract prepared from the variety of chestnuts that do grow in this area has a long history of usage in traditional Chinese medicine.

Varicose veins are a frequent and painful ailment that affects around 20-25 percent of women and 10-15 percent of males in the United States.

The veins are responsible for returning blood to the heart.

It is possible for these valves to become damaged or leak, resulting in blood pooling in the leg’s vein.

Chronic venous insufficiency is a term used to describe the condition that occurs when the veins further inside the legs are afflicted (CVI).

Despite the fact that varicose veins can be surgically removed, the most common method of therapy is compression stockings.

Studies have provided evidence.

Aescin was shown in studies to stimulate veins to contract more effectively and with more force.

Horse chestnut capsules were the subject of a systematic review, which was published in the Cochrane Library.

In this review, researchers discovered 17 randomized controlled trials using horse chestnut for CVI.

Horse chestnut was proven to be more useful than a placebo in the majority of studies.

Horse chestnut performed much better in four out of six experiments that measured leg edema.

Two trials examined the effectiveness of horse chestnut extract and compression stockings in the treatment of leg discomfort, and both concluded that they were equally beneficial.

Some persons experienced dizziness, nausea, or headaches, although these side effects only lasted a brief period of time for them.

Chestnuts contain a toxin known as aesculin, which is chemically related to warfarin and causes persistent bleeding when consumed in large quantities.

Extracts should be standardised so that it is possible to tell how much active component (aescin) is in each dosage.

Long-term studies are required due to the fact that therapy for this ailment will need to be continued for many years.

There has traditionally been a dosage of 300-600mg of extract, which is normally standardised to provide 50-100mg of aescin each dose.

Anyone on blood-thinning drugs, on the other hand, should be certain that the product they are purchasing does not include aesculin.

He holds a PhD in pharmacy, where he conducted research on herbal treatments, as well as an MA in bioethics, and he works as a senior lecturer in the School of Nursing at Dublin City University.

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