What Is Horse Chestnut Good For? (Question)

Horse chestnut extract has powerful anti-inflammatory properties and may help relieve pain and inflammation caused by chronic venous insufficiency (CVI). It may also benefit other health conditions like hemorrhoids and male infertility caused by swollen veins.

What are the health benefits of horse chestnut?

  • Anti-edematous Activity.
  • Anti-inflammatory.
  • Venotonic.
  • Post-Operative Edema.
  • Hemorrhoids.
  • Inner Ear Perfusion.
  • Herb-Drug Interactions.
  • Side Effects and Toxicity.

Does horse chestnut affect blood pressure?

Horse chestnut extract appears to impair the action of platelets (important components of blood clotting). It also inhibits a range of chemicals in the blood, including cyclo-oxygenase, lipoxygenase and a range of prostaglandins and leukotrienes. These effects result in reduced inflammation and reduced blood pressure.

How long does it take for horse chestnut to work?

It may take up to 4 weeks before your symptoms improve. Call your doctor if your symptoms do not improve, or if they get worse while using horse chestnut.

Is horse chestnut good for arthritis?

Horse chestnut leaf is used for eczema, menstrual pain, soft tissue swelling from bone fracture and sprains, cough, arthritis, and joint pain. Horse chestnut branch bark is used for malaria and dysentery. Some people apply horse chestnut branch bark to the skin for lupus and skin ulcers.

Does horse chestnut help prevent blood clots?

The seed of the horse chestnut is a small brown nut. Unprocessed horse chestnut seeds contain a toxin called esculin (also spelled aesculin). This toxin may increase the risk of bleeding due to its ability to prevent blood clots from forming.

Does horse chestnut improve circulation?

Taking 300 mg of standardized horse chestnut seed extract by mouth can reduce some symptoms of poor blood circulation, such as varicose veins, pain, tiredness, swelling in the legs, itching, and water retention. But it might be less effective than maritime pine bark for reducing leg swelling and cramps.

How do you make horse chestnut tea?

For an infusion, steep one teaspoon of horse chestnut bark in one cup of water. This tea can help treat varicose veins and other similar conditions. Decoction. Horse chestnut tea can be brewed by steeping dried leaves or bark from the tree in boiling water for several minutes.

Why is it called horse chestnut?

Etymology. The common name horse chestnut originates from the similarity of the leaves and fruits to sweet chestnuts, Castanea sativa (a tree in a different family, the Fagaceae), together with the alleged observation that the fruit or seeds could help panting or coughing horses.

Is horse chestnut good for skin?

Horse chestnut’s benefits for the skin do not stop at saponins – the seed extract contains a number of flavonoids (powerful antioxidants) such as quercetin, kaempferol, and rutin, that have demonstrated wound healing, anti-inflammatory, and anti-enzymatic properties.

What eats horse chestnuts?

There are some animals that can safely eat conkers. These include wild boars and deer. However, they are too toxic for humans to eat and will make people unwell. Strangely, despite the name horse chestnuts, they are also poisonous for horses.

Is chestnut good for thyroid?

As water chestnut contains useful minerals like iodine and manganese, it helps in maintaining proper functioning of the thyroid gland.

What happens if you eat a horse chestnut?

Toxic horse chestnuts cause serious gastrointestinal problems if consumed by humans. Consuming the nuts or leaves of horse chestnut trees causes bad colic in horses and other animals develop vomiting and abdominal pain. However, deer seem to be able to eat poisonous conkers without ill effect.

Can I use horse chestnut cream on my face?

4.0 out of 5 stars Seems to be working on my face. I’ve been using this for about a month, every day. I use it on my entire face, and on spots of spider veins on my legs.

Can you eat a horse chestnut?

While cultivated or wild sweet chestnuts are edible, horse chestnuts are toxic, and can cause digestive disorders such as abdominal pain, nausea and vomiting, or throat irritation.

Does horse chestnut cream get rid of spider veins?

Horse Chestnut This herb has long been linked to the reduction of inflammation and the strengthening of vessel walls. Like vitamin K solutions, horse chestnut may successfully disguise the appearance of spider veins due to its anti-inflammatory properties.

Is horse chestnut good for phlebitis?

Horse chestnut seed and leaf are used for treating varicose veins, hemorrhoids, and swollen veins (phlebitis). Horse chestnut seed is used for diarrhea, fever, and enlarged prostate.

What Is Horse Chestnut?

Well, Anastasia Tretiak, you’ve done really well. An Aesculus hippocastanum (horse chestnut) is a kind of tree that may be found growing across the Northern Hemisphere. Horse chestnut seed, leaves, bark, and blossoms have long been used in herbal and folk medicine to alleviate symptoms such as swelling and inflammation, as well as to strengthen blood vessel walls and to improve circulation. According to the horse chestnut’s health claims, it can be used to cure the following conditions:

  • Circulatory problems, diarrhea, hemorrhoids, and varicose veins are among conditions that might occur.

Horse chestnut includes a chemical component known as aescin, which has been shown to have anti-inflammatory effects on the body. Esculin, which is found in the unprocessed seeds, leaves, bark, and flowers, among other things, is toxic and may increase the risk of bleeding. (Aescin, on the other hand, is a separate chemical that is generally thought to be safe.) Esculin can be eliminated from the body. Esculin is removed from horse chestnut seed extract that has been properly processed.

What Is Horse Chestnut Used For?

Horse chestnut has been shown to be beneficial in the treatment of chronic venous insufficiency in humans and animals (CVI). CVI is a disorder in which the veins in the legs are unable to adequately return blood from the legs to the heart. It has been associated to issues such as varicose veins, ankle swelling, and nightly leg cramps among other things. There has been very little study done on horse chestnut for the treatment of other ailments.

Chronic Venous Insufficiency

According to recent research, horse chestnut seed extract may be beneficial in the treatment of CVI. People suffering with CVI reported reduced leg discomfort, swelling, and itching when they were given horse chestnut seed extract for a short period of time, according to a systematic evaluation of 12 clinical studies published in 2012. The researchers came to the conclusion that “the data provided shows that horse chestnut seed extract is an effective and safe short-term therapy for CVI,” according to the findings.

As reported by the National Center for Complementary and Integrative Health, there is currently insufficient data to demonstrate the positive effects of horse chestnut on disorders other than CVI.

Selection, Preparation,Storage

Never consume any part of the horse chestnut tree, including the nuts. A poisoning from the herb’s fresh, unprocessed parts (which may include its leaves, bark, or blossoms) can result in illness if consumed. Instead, spend your money on a commercial supplement. Esculin, a poisonous component of horse chestnut goods, is removed during the manufacturing process. In spite of the fact that these products are extensively used in Europe, there have been very few reports of serious side effects associated with them.

The amount of aescin in most supplements is regulated to be between 20 and 120 milligrams. Dose: 50 milligrams of aescin twice or three times a day is the most commonly prescribed dosage. Choose a delayed-release formulation if you want to avoid stomach distress.

Possible Side Effects

Horse chestnut extract has been shown to cause a variety of negative side effects, including itching, nausea, and gastrointestinal difficulties, as well as muscular pains and headaches in some people. If you’re thinking of using horse chestnut to treat CVI or any chronic health issue, talk to your doctor first to be sure you’re not doing anything harmful to your body. Horse chestnut should be avoided by people who have renal or liver problems, as well as bleeding issues. Unless under medical supervision, horse chestnut should not be used in conjunction with aspirin, Plavix (clopidogrel) and Coumadin (warfarin), or other anticoagulant or anti-platelet (blood-thinning) medicines since it may enhance the action of these treatments.

Keep in mind that there hasn’t been any research done on the safety of supplements in pregnant women, nursing mothers, children, and people who have medical issues or who are taking drugs.

Frequently Asked Questions

  • Do you know if horse chestnut is good for your kidneys? People with healthy kidneys should be able to use horse chestnut supplements in modest dosages without experiencing any adverse effects. People with renal or liver illness, on the other hand, should avoid taking horse chestnut. What is the effect of horse chestnut on your legs? A supplement containing horse chestnut seed extract may be beneficial in the treatment of chronic venous insufficiency (CVI), a circulatory disorder associated with varicose veins, ankle swelling, and nightly leg cramps. According to research, horse chestnut can help persons suffering from CVI with their leg discomfort, swelling, and itching. Is horse chestnut a dangerous plant to eat? Yes, horse chestnut in its raw, uncooked form may be lethal. Ingesting unprocessed portions of the horse chestnut tree, such as the leaves, bark, or blossoms, can result in illness and perhaps poisoning if done so repeatedly. Esculin, a toxic substance found in the horse chestnut tree, is responsible for the tree’s deadly properties. Supplements sold in stores have been treated to eliminate esculin and are thus safe to take.

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Horse chestnut Uses, Side Effects & Warnings

Horse chestnut is the generic name for this plant (HORSE CHEST nut) Venastat is the brand name for this product. Oral capsules are the most common dosage type (300 mg) Herbal products are a type of medication.

  • Indications, precautions, and instructions
  • What to avoid
  • Side effects and interactions

What is horse chestnut?

Aescin, Aesculus hippocastanum, Castao de Indias, Châtaignier de Mer, Châtaignier des Chevaux, Escine, Faux-Châtaignier, Hippocastani, Hippocastanum Vulgare Gaertn, Marron Europeen, Marronnier, Spanish Chestnut, Venostasin Retard, Venostat, White Chestnut, and other names are all used to describe this Equine chestnut has traditionally been utilized in alternative medicine, and it is believed to be useful in alleviating some signs and symptoms associated with chronic venous insufficiency (decreased blood flow return from the feet and legs back to the heart).

  • Leg soreness or tenderness, varicose veins, itching or swelling in the legs, and fluid retention are some of the signs of this condition (puffy or swollen ankles or feet).
  • It is not known whether horse chestnut is beneficial in the treatment of any medical disease, including cancer.
  • In addition, horse chestnut should not be substituted for any prescription recommended by your doctor.
  • Because there are currently no controlled manufacturing standards in place for a large number of herbal substances, several advertised supplements have been found to be contaminated with harmful metals or other medications.

The purchase of herbal/health supplements should be made from a reputable supplier in order to reduce the danger of contamination. Horse chestnut can be used for a variety of other uses that are not covered in this product reference.


All product labeling and packaging instructions must be followed. Inform each of your healthcare providers about all of your medical problems, allergies, and medications that you are currently taking.

Before taking this medicine

Consult your healthcare physician before beginning to use horse chestnut. If you have specific medical issues, such as the following, you may not be able to utilize horse chestnut:

  • Consult with your healthcare physician before using horse chestnut. Certain medical disorders, such as the following, may prevent you from using horse chestnut:

Uncertainty exists as to whether horse chestnut will do damage to an unborn child. If you are pregnant, you should avoid using this product. Horse chestnut has the potential to transfer into breast milk, causing damage to a breastfeeding baby. If you are breast-feeding a child, you should avoid using this product. Do not offer any herbal or health supplement to a child unless you have obtained medical advice beforehand.

How should I use horse chestnut?

In the event that you are considering the use of herbal supplements, consult with your doctor first. You could also think about talking with a practitioner who is well-versed in the usage of herbal remedies and health supplements. If you decide to use horse chestnut, follow the directions on the container or those given to you by your doctor, pharmacist, or other healthcare practitioner. Make sure you do not use more of this product than what is indicated on the package. If you take horse chestnut in capsule form, the normal dose is 1 capsule every 12 hours before a meal before bed.

  • Horse chestnut capsules should not be crushed, chewed, broken, or opened in any way.
  • Use a horse chestnut product that includes an exact amount of the stated ingredient in order to achieve the greatest results.
  • It might take up to 4 weeks for your symptoms to begin to ease.
  • Moisture, heat, and light should all be avoided when storing this product.
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What happens if I miss a dose?

If it is almost time for your next scheduled dosage, you should skip the missed dose. It is not necessary to take more horse chestnut to make up for the missing dose.

What happens if I overdose?

Seek immediate medical treatment or dial 1-800-222-1222 to reach the Poison Help hotline for assistance. The usage of raw horse chestnut (seeds, blossoms, stems, and leaves) can result in deadly toxicity if consumed in large quantities. Strength, low mood, loss of coordination, dilated pupils, vomiting and diarrhea, infrequent or no urination, muscular twitching, and loss of mobility in any region of the body are all possible symptoms of horse chestnut poisoning.

What should I avoid while taking horse chestnut?

Raw horse chestnut seed, bark, blossom, or leaves should be avoided at all costs. These products are not safe to consume orally and may have potentially catastrophic negative effects. Horse chestnut should not be taken in conjunction with other herbal/health supplements that might reduce blood sugar levels, such as alpha-lipoic acid, chromium, devil’s claw, fenugreek, garlic, guar gum, Panaxginseng, psyllium, and Siberian ginseng, among others. It is best not to use horse chestnut with other herbs or health supplements that might interfere with blood clotting time.

Angelica (dong quai), capsicum, clove, danshen, garlic, ginger, ginkgo, panax ginseng, poplar, red clover, turmeric, and willow are some of the herbs used in traditional Chinese medicine.

Horse chestnut side effects

If you have any of the following symptoms of an allergic reaction, get medical attention immediately: hives; difficulty breathing; swelling of your face, lips, tongue, or neck. Horse chestnut is regarded to be potentially harmless when consumed for a short length of time, despite the fact that not all of its adverse effects are known. If you develop any of the following symptoms, stop taking horse chestnut and contact your healthcare professional right away: The following are examples of common side effects: The following is not a comprehensive list of possible side effects, and more may occur.

You can report adverse effects to the Food and Drug Administration at 1-800-FDA-1088.

What other drugs will affect horse chestnut?

If you are using any of the drugs listed below, you should not take horse chestnut without seeing your doctor first.

  • In addition to insulin or an oral diabetes medication, you may need blood clot-prevention medications such as clopidogrel (Plavix), dabigatran (Enoxaparin), heparin (Coumadin, Jantoven), and others
  • Or an NSAID (nonsteroidal anti-inflammatory drug) such as aspirin, ibuprofen (Advil,Motrin), naproxen (Aleve), celecoxib (dic

This is not an exhaustive list. Other medications, including prescription and over-the-counter medications, vitamins, and herbal supplements, may have an adverse reaction with horse chestnut. This product guide does not provide a comprehensive list of all potential interactions.

Further information

  • If you are considering utilizing any herbal or health supplement, consult with a registered healthcare expert first. In order to ensure that all of your healthcare providers are aware of all of your medical issues and medications, whether you are being treated by a medical doctor or a practitioner educated in the use of natural medicines/supplements, you should:

Remember to keep this and all other medications out of the reach of children, never share your medications with others, and only use this drug for the indication that has been given for it. Always check with your healthcare practitioner to confirm that the information contained on this page is accurate and applicable to your specific situation. Disclaimer on Medical ImplicationsCopyright 1996-2022 Cerner Multum, Inc. version 3.02 is available.

Horse Chestnut (Venastat) – Side Effects, Interactions, Uses, Dosage, Warnings

Aescin, Aesculus hippocastanum, Castao de Indias, Châtaignier de Mer, Châtaignier des Chevaux, Escine, Faux-Châtaignier, Hippocastani, Hippocastanum Vulgare Gaertn, Marron Europeen, Marronnier, Spanish Chestnut, Venostasin Retard, Venostat, White Chestnut, and other names are all used to describe this Horse chestnut has been used in alternative medicine for centuries and is likely to be useful in treating some of the symptoms of chronic venous insufficiency, according to some studies (decreased blood flow return from the feet and legs back to the heart).

  1. Leg soreness or tenderness, varicose veins, itching or swelling in the legs, and fluid retention are some of the signs and symptoms of this condition (puffy or swollen ankles or feet).
  2. It is not known whether horse chestnut is beneficial in the treatment of any medical disease, including cancer.
  3. In addition, horse chestnut should not be substituted for any prescription recommended by your doctor.
  4. Because there are currently no controlled manufacturing standards in place for a large number of herbal substances, several advertised supplements have been found to be contaminated with harmful metals or other medications.

The purchase of herbal/health supplements should be made from a reputable supplier in order to reduce the danger of contamination. Horse chestnut can be used for a variety of other uses that are not covered in this product reference.

Horse Chestnut

Please inform your healthcare professionals if you are taking any dietary supplements, such as herbal supplements, vitamins, minerals, or natural or homeopathic medicines. This will assist them in managing your care and ensuring your safety. Horse chestnut has been demonstrated to be useful in the treatment of chronic venous insufficiency, although it is not known what its long-term consequences are. Horse chestnut extract is made from the seeds of the plant. Aescin is one of its active ingredients, and it has been shown to decrease inflammation and raise the tone of veins.

Additionally, the presence of other substances in horse chestnut seems to enhance the tone of blood vessels while decreasing their permeability.

Aesculetin, a chemical found in horse chestnut, may have anticoagulant and blood thinner properties, and as a result, it is frequently omitted from over-the-counter horse chestnut products.

  • To alleviate the symptoms of circulatory diseases Several clinical research have shown that horse chestnut can be used as a short-term therapy for CVI, however the long-term consequences of horse chestnut remain unclear. In order to cure phlebitis There is no scientific evidence to justify this practice. In order to cure varicose veins, This assertion is not supported by any evidence
  • In order to treat diarrhea There is no scientific evidence to support this assertion
  • Thus, it is incorrect. In order to cure hemorrhoids There is no evidence to support this claim
  • The FDA has designated horse chestnut seed as a potentially dangerous botanical. Many of the chemicals found in horse chestnut are regarded to be harmful
  • However, this is not always the case.
  • If you are on warfarin, aspirin, or other blood thinners, you should see your doctor. Aesculin is included in several horse chestnut products, which may increase the risk of bleeding. Examine the label to ensure that your horse chestnut product is devoid of aesculin. You are taking medications that are substrates for Cytochrome P450 enzymes, such as the following: Horse chestnut has been shown to enhance the negative effects of prescription medications as well as impair their efficacy.

Poisoning from horse chestnut can include diarrhea, muscular twitching, dilated pupils, depression, and paralysis when taken in large amounts. Reports on Individual Cases

  • Horse chestnut intake has been linked to intestinal blockages in many cases, necessitating surgical removal in a few cases. A life-threatening kidney rupture occurred in a patient with a benign kidney tumor who had been taking horse chestnut seed extract for venous insufficiency when the rupture occurred. Inflammation in the area of the heart and difficulty breathing: Within six weeks, the patient, a 32-year-old guy, had ingested three boxes of horse chestnut paste.

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For Healthcare Professionals

Horse chestnut, a tree endemic to the Balkan Peninsula that has been utilized in traditional medicine for hundreds of years, is a good example of this. The seed extract is used orally as a dietary supplement to help maintain normal blood vessel function. Horse chestnut and sweet chestnut are not to be mistaken with one another. It has been shown in laboratory tests that the chemical in horse chestnut known as escin, or aescin for short, has anti-inflammatory1, neuroprotective1, and antitumor(2)(3) properties, and that it increases the effectiveness of the anticancer drug gemcitabine (18).

Horse chestnut extract is a safe and well tolerated therapy for CVI(6)(7)(8), according to systematic reviews and meta-analyses; however, a Cochrane review of rutosides found no clear evidence of efficacy for post-thrombotic syndrome (PTS) (11).

Consumption of horse chestnut products is not recommended for those with impaired renal or hepatic function.

  • Circulatory problems, phlebitis, varicose veins, diarrhea, and hemorrhoids are all possible.

A natural mixture of triterpenoid saponins, known as Escin or Aescin, isolated from the seed of the horse chestnut, has been identified as the active component. Escin, also known as Aescin, is a natural mixture of triterpenoid saponins. It is believed that escin’s anti-inflammatory actions are mediated by a considerable downregulation of the expression of certain inflammatory genes and an increase of the production of granulocyte-macrophage colony-stimulating factor (GM-CSF), which also has neuroprotective properties (1).

This is one of several mechanisms by which escin works to alleviate chronic venous insufficiency (19).

SMMC-7721 cells from patients with hepatocellular carcinoma were found to be resistant to beta-aescin and 5-fluorouracil, which may be due to the synergistic effects of the drugs, which include cell-cycle arrest, induction of apoptosis, activation of caspases-3, 8 and 9, and down-regulation of Bcl-2 expression (17).

In the United States, horse chestnut seeds are classed as dangerous by the FDA due of the harmful effects they have on the body.

Chestnut poisoning manifests itself in the following symptoms: diarrhea, muscular twitching, dilated pupils, depression, and paralysis (14).

In the case of bezoars, surgical removal was required(15)(12) in certain cases (13).

Following an emergency embolization, the patient’s symptoms improved (16). Pericarditis and dyspnea were seen in a 32-year-old male who had taken three boxes of horse chestnut paste over a six-week period, according to the study (14).

  • Anticoagulants and antiplatelet agents: Horse chestnut, which contains aesculin, a hydroxycoumarin(9), may have an additional anticoagulant effect owing to its coumarin content. CYP1A2, CYP2C9, and CYP3A4 enzymes have been demonstrated to both inhibit and stimulate their respective CYP1A2, CYP2C9, and CYP3A4 enzymes in an animal research, suggesting that Aescin may change the intracellular concentration of medicines metabolized by these enzymes (22). The clinical significance of this study has not yet been identified.

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Horse Chestnut

HORSE CHESTNUT, also known as buckeye and Spanish chestnut, is a kind of tree whose fruits (seeds, leaves, bark, and blossoms) have been used medicinally for thousands of years. The trees are native to Eastern Europe, however they may be found all across the Northern Hemisphere due to their widespread distribution. It is commonly called to as buckeye, however it is not the same species as buckeye trees that grow in Ohio and California, despite the fact that it looks similar. Horse chestnut seed extract has been widely explored for the treatment of chronic venous insufficiency (CVI), a circulatory disorder in which the veins fail to adequately return blood from the legs to the heart (see below).

Varicose veins are also present.

According to one research, it is just as efficient as compression stockings in terms of reducing swelling.

Symptoms of discomfort, itching, burning, and swelling were greatly reduced in one small trial that used horse chestnut extract.

Aescin extracts standardized to contain 16 to 20% aescin are available in the following forms: Interactions between herbs and medications: The use of horse chestnut extract may cause bruising and bleeding in patients who are taking aspirin, ibuprofen, coumadin, or other medicines that reduce blood coagulation, according to the American College of Nutrition.

  1. Lithium is a medication used to treat the manic phase of the disease.
  2. Horse chestnut has been shown to reduce blood sugar levels in diabetics, which may enhance the benefits of diabetes medications that lower blood sugar levels.
  3. Aesculin is a compound in horse chestnut seeds, leaves, bark, and flowers that is poisonous if consumed in teas or remedies made with raw or unprocessed horse chestnut seeds, leaves, bark, or flowers.
  4. It is believed that horse chestnut seed extract, when properly processed, has little or no aesculin and is hence safe for short-term usage.
  5. It has not been determined whether or whether using horse chestnut is safe for women who are pregnant or who are nursing.
  6. Purchase items with an aescin level of 16 to 20% and follow the guidelines on the label when preparing meals or cooking.
  7. Dosage for children: It has not been determined whether horse chestnut is safe for youngsters to consume.
  8. Weil explains.
  9. The chemical aescin is regarded to be the primary active element in HCSE, as it contributes to the maintenance of normal vessel-wall function.
  10. The active components in the seeds appear to prevent enzymes that might cause damage to capillary walls, which in turn appears to help strengthen veins.
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SOURCES: nccam.nih.gov/health/horsechestnutmed.nyu.edu/content?ChunkIID=21758naturaldatabaseconsumer.therapeuticresearch.com/nd/Search.aspx?rn=3 nccam.nih.gov/health/horsechestnutmed.nyu.edu/content?ChunkIID=21758naturaldatabaseconsumer cs=NONMP s=NDC pt=100 id=1055 fs=NDC searchid=45802997 s=NDC pt=100 id=1055 s=NDC searchid=45802997 J.

  • Gillet, J.M.
  • Defrance.
  • Rev Med Liege 1976;31:343–345 (in French).
  • Pittler MH, Ernst E.
  • Cochrane Database Syst Rev.
  • Natural Medicines Comprehensive Database, naturaldatabaseconsumer.therapeuticresearch.com, accessed March 27, 2014.

Horse chestnut. Natural Medicines Comprehensive Database, accessed March 27, 2014. New York University Langone Medical Center’s Principle Proposed Usages for Horse Chestnut The 27th of March, 2014

Horse Chestnut Seed Extract: Benefits & Uses

In addition to horse chestnut, it is known by numerous other names, including aesculus hippocastanum (also known as buckeye), conker tree (also known as marronnier), and venostat (also known as venostat). Despite the fact that they are always referred to as “horse chestnut,” the plant with which we are concerned is aesculus hippocastanum. The seeds and extracts from these trees, which are native to the Balkan peninsula, are utilized as nutritional supplements and have become fairly popular as a result of the health advantages they provide.

We’ll go through the benefits, how it works with venous insufficiency, adverse effects, and other details of this medication.

Uses Of Horse Chestnut Extract

It is not only the horse chestnut seed that has health-promoting properties. There are a variety of remedies and ointments that employ the bark, flower, and leaves of this plant. However, there is a word of warning. Horse chestnut contains minute levels of esculin, a toxin that is toxic in small doses. It is potentially lethal if consumed uncooked. Medications derived from the seeds and leaves of the plant are used to treat varicose veins, hemorrhoids, and phlebitis, among other conditions. The seeds can also be used to treat other conditions such as diarrhea, fever, and an enlarged prostate gland.

  • As a result of its anti-inflammatory characteristics, the extract can be utilized to treat a variety of circulatory issues, including chronic venous insufficiency. It is also used to treat a variety of conditions such as menstruation cramps, eczema, cough, joint discomfort, and arthritis. The bark can be used to treat diarrhea, malaria, lupus, and ulcers, among other things.

Venous InsufficiencyHorse Chestnut

Known medically as venous insufficiency, this cardiovascular problem leads in decreased blood flow to one’s extremities, particularly the legs. Doctors recommend that patients suffering from venous insufficiency wear compression socks, which assist to enhance blood flow to the legs and promote healthy blood circulation. The following are some of the signs and symptoms of venous insufficiency:

  • Edema or swelling in the legs
  • Leg cramps
  • Varicose veins
  • Numbness and tingling in the lower legs
  • Leg ulcers

Using Horse Chestnut to Treat Venous Insufficiency

In Horse Chestnut seed extract, there is a component called aescin, which contains anti-inflammatory and other qualities that can help to enhance blood circulation. Patients who suffer from venous insufficiency may find this extract to be of use to them. The results of studies reveal that patients who took a 300mg horse chestnut extract twice a day for eight weeks, which includes around 50 mg of the anti-inflammatory compound aescin, had a reduction in their symptoms. Irritation and discomfort were also lessened as a result of the treatment.

How Does It Work?

The aescin that we discussed before is a blood-thinning agent that results in increased blood flow in the body. It is also a moderate diuretic, which means that it aids in the removal of fluid from the body through the urine. It aids in the drainage of edemas by reducing water retention.

Is There Anything to Worry About?

An example of this is aescin, which is a blood-thinning agent that promotes enhanced blood circulation.

A moderate diuretic, it aids in the removal of excess fluid from the body through the kidneys. It helps to discharge edemas by reducing water retention.

When to Not Take Horse Chestnut Extract

  • If you are pregnant or nursing, please do not use this form. There isn’t enough information available to determine how the supplement may effect newborn newborns and fetuses at this time. It’s ideal if you can avoid taking the supplement altogether. Disorder of bleeding. Aescin is a medication that thins the blood, which can be extremely harmful for someone who already has a bleeding issue. Diabetic. Horse chestnut has been shown to reduce blood sugar levels, which can result in issues such as digestive/kidney difficulties or liver illness. There have been reports of horse chestnut extract having a negative impact on the health of people suffering from certain conditions. Surgery. If you are going to have surgery soon, you should avoid taking the supplement at all costs. The component in horse chestnut extract that thins the blood can be extremely harmful for a patient who is undergoing surgery.

What Medicines Can Interact with Horse Chestnut Extract?

Lithium. Whether or whether you are using a medicine that includes Lithium, you should consult with your health care practitioner before taking horse chestnut supplement. A possible side effect of the supplement’s diuretic component is that it might alter the way lithium is absorbed and eliminated by the body. Medications for Type 2 Diabetes. Because horse chestnut extract has been shown to reduce blood sugar levels, when used with diabetic medications, it has the potential to induce dangerously low blood sugar levels.

These are medications that thin the blood and help to keep the blood from clotting.

Some Last Thoughts about Horse Chestnut Extract

Horse chestnut extract has been demonstrated to be useful in the treatment of chronic venous insufficiency, according to recent research findings. It has the potential to alleviate symptoms and control discomfort. The product’s long-term consequences, on the other hand, remain unclear. It’s essential to proceed with caution and keep an eye out for any negative side effects that may occur. If you encounter any adverse effects, you should contact your doctor immediately. Do not begin taking horse chestnut extract until you have spoken with your doctor about it first.

While horse chestnut extract may be beneficial in alleviating your venous symptoms, it is not a treatment for the condition.

If the need arises, our medical specialists can assist you in determining the most appropriate treatment option for your venous insufficiency.

Horse chestnut seed extract for long-term or chronic venous insufficiency

Conclusions of the authors: Based on the evidence given, HCSE appears to be an effective and safe short-term therapy for CVI. Many limitations remain, and bigger, definitive randomized controlled trials are needed to prove the effectiveness of this therapy approach. See the complete abstract for more information. Background: The conservative treatment of chronic venous insufficiency (CVI) relies mostly in the use of compression. However, this frequently causes pain and has been linked to lower levels of patient compliance.

  1. Presented below is an updated version of a Cochrane review that was initially published in 2002 and has since been revised in 2004, 2006, 2008, and 2010.
  2. The following is the search strategy: The Cochrane Peripheral Vascular Diseases Review Group checked their Specialised Register (which was last searched in June 2012) and the CENTRAL database for this update (Issue 5, 2012).
  3. HCSE preparation manufacturers and subject matter experts were approached for both published and unpublished material on the subject of HCSE.
  4. The following are the selection criteria: Randomized controlled trials comparing oral HCSE mono-preparations with placebo or reference treatment in persons with CVI were conducted.
  5. Data collection and analysis are two important aspects of every research project.
  6. Through dialogue, disagreements on the assessment of particular experiments were addressed.
  7. Leg pain was evaluated in seven randomized, placebo-controlled studies.
  8. The results of one study indicated a weighted mean difference (WMD) of 42.4 mm (95% confidence interval (CI) 34.9 to 49.9) when assessed on a 100 mm visual analogue scale.
  9. A WMD of 32.1ml (95 percent confidence interval: 13.49 to 50.72) was seen in six studies (n = 502) in favor of HCSE when compared to placebo.

According to the results of one study, HCSE may be just as effective as therapy with compression stockings. The majority of adverse effects were moderate and uncommon.

Horse Chestnut Benefits – Using Horse Chestnut Trees And Conkers

Tonya Barnett contributed to this article (Author ofFRESHCUTKY) Horse chestnut trees, while typically seen in landscape plantings in yards and along city streets, have long been prized for their aesthetic appeal as well as their practicality. Horse chestnut has been used for a variety of purposes throughout history, which is rather astounding. It is simple to understand why the cultivation of horse chestnut trees has expanded around the world, owing to their usage as superb shade trees and the potential health advantages they may provide.

What is Horse Chestnut Used For?

First and foremost, horse chestnut trees vary from ordinary ” chestnut” trees in several ways. This well-known moniker frequently causes a great deal of misunderstanding. All portions of the horse chestnut tree, Aesculus hippocastanum, are very poisonous to humans and should not be consumed by them in any form. Esculin, a deadly toxin found in horse chestnuts, is responsible for their lethal nature. When this hazardous drug is consumed, it can result in major problems and even death. Toxins can only be eliminated from food by proper preparation and processing.

  • This procedure cannot be carried out at home.
  • Many people believe it can be used to cure a variety of disorders and are in favor of it.
  • In addition, it is crucial to remember that the Food and Drug Administration has not examined any of these claims (FDA).
  • Additionally, people who are on any other drugs should always get the advice of a skilled physician before using horse chestnut extract.

Horse Chestnut Supplement Uses & Health Benefits

However, while horse chestnut cannot be cooked over an open fire, you may be interested to hear that it is a highly powerful nutritional supplement that has been used for hundreds of years to heal a variety of ailments. Individuals have traditionally consumed horse chestnut in hopes of treating joint pain, bladder and intestinal difficulties, fever, or leg cramps without the use of pharmaceuticals. Horse chestnut has a number of advantages, some of which have not been shown scientifically. These include its capacity to treat chronic venous insufficiency (a vascular problem), hemorrhoids, and edema following surgery, among other things.

The benefits of horse chestnut extract include a high antioxidant content, the potential to be a male fertility aid, and early indications that the extract may be able to destroy some types of cancer cells.

6 Benefits of Horse Chestnut Seed Extract

Chronic Venous Insufficiency, also known as post-thrombotic syndrome or phlebitis, is a condition that affects the veins of the legs. This disorder is characterized by non-functioning valves in your veins (often in the legs and arms), which causes blood to pool in the limbs and a rise in internal pressure inside the veins, causing swelling and pain in the limbs. CVI is really a highly prevalent condition, affecting as many as 40% of the population in the United States at one time. Women, particularly those who have had numerous pregnancies, as well as middle-aged and older persons, are more likely to be affected.

Compression therapy is often used in the conventional medical treatment of chronic venous insufficiency, which many patients dislike because of the discomfort it causes.

However, the reviewers cautioned that larger and more conclusive studies must be conducted before any conclusions can be drawn.

2. Could Cause Cell Death in Certain Cancers

For example, when scientists do cancer research on a specific chemical, they begin by studying the effect of that drug on certain types of cancer cells in a laboratory setting. When a drug has a considerable impact on the death of those cancer cells, further investigation may be necessary to determine whether or not it is a potentially effective cancer treatment. Horse chestnut extract has been proven to have cancer-fighting properties in a laboratory environment when tested on cells associated with leukemia, cervical cancer, and breast cancer.

The lab tests revealed that the cells died at a rate of approximately 94 percent in these cells.

3. Contains Powerful Antioxidants

Horse chestnut extract has some powerful antioxidants that can assist your body in fighting free radical damage and fighting illness more efficiently than any other food. Horse chestnut has been shown to contain both quercetin and kaempferolglycosides, which are powerful antioxidants known for their disease-fighting qualities. (6) Additionally, a research conducted on animals discovered that horse chestnut may be able to prevent the body’s loss of glutathione, another antioxidant, following liver damage.

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4. May Increase Effects of Prebiotics

Many of us are aware that healthy probiotic meals may help with digestion and gut health, but did you know that by combining probiotic foods with prebiotics, you can reap even greater digestive benefits? Prebiotics are a sort of non-digestible fiber component that is fermented by the gut microorganisms in the colon, and they are beneficial to the body. Horse chestnut extract and flaxseed oil were used in a study done in 2011 on rats to determine the efficacy of employing these two ingredients to enhance the impact of probiotics.

Both of these natural compounds increased the effectiveness of prebiotics. Prebiotics, according to the scientists who conducted the study, are beneficial agents in the prevention and treatment of colon cancer. (8)

5. Possibly Beneficial in Wound Healing

Another advantage of horse chestnut that has emerged as a result of preliminary study is its potential to speed the healing of wounds. A 2006 laboratory research discovered that horse chestnut extract can aid in the induction of contraction forces in fibroblasts, which are cells that are essential in the wound healing process. However, no human trials have yet been undertaken. (9) When these fibroblasts contract, they have the ability to speed up the healing of wounds. Again, this research is not definitive, and it is possible that the results will not work as intended in people, but the first findings are encouraging.

6. Might Support Fertility in Men

Male infertility is developing at a faster rate than ever, and understanding how to support and maintain high sperm counts has become more crucial than ever. (10) Horse chestnut supplements include a component known as escin, which should not be mistaken with the deadly esculin found in raw horse chestnuts, which is toxic. Escine appears to safely increase the number and quality of sperm in men who have varicocele-associated infertility, according to a 2010 research study. The mechanism by which escin appears to work is possibly the same as the mechanism by which horse chestnut has a positive impact on chronic venous insufficiency.


What Are Horse Chestnuts?

Firstly, horse chestnuts are not related to chestnuts at all; they belong to a completely distinct family of plants and shrubs known as the Hippocastanaceae, which means “horse chestnut family.” While there are 15 known species of horse chestnut, the European horse chestnut (Aesculus hippocastanum) is the most regularly seen species in supplementary and herbal medicine applications. Horse chestnuts are coated in a prickly, greenish outer covering on the tree, and they fall to the ground as the lustrous, brown fruit that was previously mistaken for a type of chestnut by the ancients.

(13) Horse chestnuts are not suitable for consumption by humans due to the glycosides and saponins contained in them, respectively.

HistoryInteresting Facts about Horse Chestnut

Horse chestnuts, in their most common form, are native to the Balkans, although they may now be found in all temperate zones of the Northern Hemisphere. However, you may hear this referred to by a variety of different names; for example, horse chestnuts that are native to the United States are referred to as “buckeyes.” Known as conker trees in other parts of the world, they are particularly popular in the United Kingdom. Conkersis a popular autumn game in which you thread yarn through horse chestnuts and take turns striking the conker of your opponent.

According to some reports, the two million trees that exist in the United Kingdom now may be gone by 2031.

(15) Although the horse chestnut tree was described in a letter sent in 1557, it wasn’t extensively recognized or appreciated until the nineteenth century.

Despite the fact that the origin of the term “horse chestnut” is commonly attributed to its usage with horses, another possible contributing cause is the fact that the leaf stalk, when it falls, creates a “scar” on the tree that resembles an inverted horseshoe with nail holes. (17)

How to Use Horse Chestnut Extract

Horse chestnut is often recommended in supplement form at levels ranging from 400 to 600 mg per day, split into two doses spaced 12 hours apart. However, the escin component (the active molecule) is far more essential, and it should be taken in doses of 100–150 milligrams each day. The horse chestnut cream, which may be applied directly to troublesome vein regions, as well as a combination horse chestnut/broom butcher’s cream for varicose veins or hemorrhoids, are both available from some suppliers (18).

Possible Side EffectsPrecautions

As previously stated, you should never consume horse chestnut fruits that have fallen from the tree since they are poisonous. They contain esculin, a toxic chemical that has the potential to induce bleeding. Horse chestnut, in its processed form, devoid of esculin, is considered safe for most individuals to consume for short periods of time. There have been no long-term studies on the safety of this medication. Itching, nausea, gastrointestinal distress, muscular spasms, and headaches are some of the more prevalent adverse effects that may occur (although they are quite rare).

  • Pregnant or breastfeeding moms (since there is little data to support their safety)
  • Bleeding problems (which might result in sluggish clotting)
  • Diabetes (which can result in reduced blood sugar)
  • Digestive issues (may cause irritation to the GI tract)
  • Individuals with latex allergy (who may also be allergic to horse chestnut) should see their physician. The following conditions may increase symptoms: liver illness (which may exacerbate symptoms)
  • Kidney disease (which may intensify symptoms)
  • Procedures such as surgery (which may impair appropriate blood flow and clotting either before or after the procedure)

Expectant or breastfeeding women (since there is little data to support their safety). Those suffering from bleeding issues (which might result in sluggish clotting); those suffering from diabetes (which can result in reduced blood sugar); Gastrointestinal tract irritation (may cause GI tract irritation). Allergic reaction to latex (people who have this reaction may also be allergic to horse chestnut); The following conditions may increase symptoms: liver illness (which may exacerbate symptoms); kidney disease (which may intensify symptoms).

  • It is used in lithium, diabetes drugs, anticoagulants (it induces vein/artery constriction in cows and lowers platelet aggregation in humans, both of which can result in bleeding) (20).

There have been a few reports of additional problems associated with the use of horse chestnut extract. To name a few examples, there is a case report of a 32-year-old man who experienced acute profuse pericarditis after consuming horse chestnut. (21) Another case report demonstrates a relationship between horse chestnut extract and renal angiomyolipoma (renal AML), a benign fatty tumor of the kidney that can be treated with surgery. Horse chestnut is not recommended for people suffering from this illness, according to the paper.

Horse Chestnut Key Points

  • Chronic venous insufficiency, a problem with vein pressure sometimes preceded by varicose veins and/or blood clots, affects up to 40% of the population in the United States, and horse chestnut has been shown to be beneficial in treating this condition. However, there are valid precautions to take into consideration when using this fantastic nutritional supplement, including possible side effects and prescription interactions, as well as hazards for pregnant or nursing women and persons with specific health issues. Before beginning a new supplement regimen, thoroughly investigate the dangers listed above and check with your health care practitioner.

6 Horse Chestnut Seed Extract Benefits

  1. It may be useful in the treatment of chronic venous insufficiency
  2. It has the potential to trigger cell death in some malignancies. Has a high concentration of strong antioxidants
  3. Prebiotics have the potential to enhance their effects. It is possible that it will be effective in wound healing. Men’s fertility may be supported by this supplement.

Read Next:Yuzu Fruit: 6 Health Benefits of a Unique Citrus Fruit

Horse Chestnut is a kind of tree that may be found throughout Europe and the United States of America. The bark from young branches and the seeds of the tree are the parts of the tree that are utilized in medicine. The seeds that are found inside the fruit are seen in the image below. If the seeds are not processed, they are toxic. Aescin, on the other hand, is one of the compounds contained in horse chestnut seed. It is the compound Aescin, which is isolated from the horse chestnut seed, that may be beneficial for circulatory health.

How Does Horse Chestnut Treat Varicose Veins?

Aescin has three effects that are beneficial in the treatment of symptoms of venous insufficiency.

  • First and foremost, it reduces edema or swelling. Chronic venous insufficiency leads in capillary leakage of plasma fluid as a result of elevated venous pressure in the legs. Edema or swelling occurs as a result of this leak. Aescin has a “sealing” effect on tiny blood vessels
  • Second, it has anti-inflammatory properties as well. Aescin operates at the cellular level to inhibit the release of inflammatory mediators
  • Finally, it enhances the tone of the veins and capillaries. When exposed to Aescin, the smooth muscle in normal vein walls contracts, indicating that the vein is healthy.

Does Horse Chestnut really work to treat Varicose Veins?

Most likely, yeah. Horse chestnut extract, when compared to a placebo (a sugar tablet), has been shown to provide a substantial reduction in pain in randomized experiments (see below). Furthermore, the majority of the trials have shown a reduction in edema as well. Another research of venous stasis ulcer patients found no improvement with Aescin, despite the fact that the drug was prescribed. As a result, it is suggested that Horse Chestnut is less helpful when the condition is advanced.

There are so many different preparations of Horse Chestnut, which one is best?

  • The pill is the form that has been examined the most. Creams and lotions have poor absorption through the skin and are thus not suggested
  • Look for the active component Aescin in these formulations. The recommended daily dose of Aescin is around 100-150mg divided into two doses. This is when a little math comes into play. If the preparation contains 300 mg of Horse Chestnut and the amount of Aescin is 20%, it equates to 60 mg of Aescin per tablet. Dietary supplements are not regulated by the FDA. Therefore, search for a supplement that has been manufactured according to Good Manufacturing Practices (GMP).

So, Horse Chestnut works, why not use it?

  • Using horse chestnut for more than 6 months is not suggested because it has a limited half-life. Using Horse Chestnut to treat chronic venous insufficiency merely serves to delay the need for a more permanent solution
  • Horse Chestnut does not appear to be effective in treating severe illness, which is a concern. When the illness progresses, vessel wall deterioration develops, and fibrous tissue takes the place of the muscles. Aescin, on the other hand, will alleviate the symptoms of chronic venous insufficiency by boosting venous tone and avoiding leaks. When you have varicose veins, you will experience swelling, discomfort, and itching. Aescin does not necessarily improve one’s look
  • After all, it is a pharmaceutical product. Despite the fact that it is a supplement and that it originates from nature, it has been synthesized into an active chemical and is thus classified as a drug. This is similar to opium and other drugs, which are derived from poppy seeds and processed into pills. Additionally, it is similar to aspirin, which was initially derived from willow bark. As a result, as with any medication, you should consult with your doctor before using it.

Bottom Line

Horse Chestnut extract is effective in alleviating the symptoms of chronic venous insufficiency when used on a short-term basis. Horse Chestnut extract, on the other hand, will not assist with advanced sickness. Horse Chestnut extract, on the other hand, is a pharmaceutical. Consult your doctor before using this product.


A study of horse-chestnut seed extract for chronic venous insufficiency was conducted by Pittler and Ernst. A criterion-based systematic review was conducted. Arch Dermatol. 1998 Nov;134(11):1356-1360 [Arch Dermatol]. B Human varicose saphenous veins respond to vasoactive agents in the presence of runner’s factor (F), Christine (H), and Schuller-Petrovic (S). The British Journal of Clinical Pharmacology published a paper in March 2001 titled “Br J Clin Pharmacol 51(3):219-224.” Clinical effectiveness of horsechestnut seed extract in the treatment of venous ulcers, Leach MJ, Pincombe J, Foster G, Journal of Medicinal Food, vol.

Sirtori C.

Pharmacological Research, vol.

3, pp.

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